Structural genomics is a worldwide effort at determining the three dimensional structure of gene products.
The key to structural genomics is to group proteins into families of similar structural, based on their sequences. Then, based on the known structure of at least one protein in a family, and using a computational technique, a good guess can be made about the shapes of other proteins in family.
Estimates of the number of protein structure families range from 30,000 to 50,000! Structure genomics can play an important role in discovering new drugs.